PepOSX   |  Peptidomics exploration

PepOSX , a  professional  assistant for peptidomics 

Focusing on the free peptide identification, equipped with a robust sample manager and multiple identification engines, supporting cross-sample identification, XIC view, source sequence analysis, PI, hydrophobicity analysis, and bioactive peptide matching.


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multiple engines | 多引擎

Equiped with Exhaust, Search and AIDenovo (developing) engines, focusing on free peptide identification.

配备Exhaust, Search and AIDenovo (调试中)引擎,专注游离多肽鉴定。

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Identify peptides across samples | 跨样品鉴定多肽

Identify peptides from across samples with integrated XIC, track the variation.


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Sequence Analysis | 序列分析

Sequence statical analysis to look for the target peptides.


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More you want | 更多

XIC、PI、Gravy、Bioactivity analysis               


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Serve more than 40 research groups


Serve to ... 

ZHeJiang University, Jilin University, South China University of technology, Chinese academy of sciences, etc..



Research Paper, please cite the work as : 

[1] Liu, W., Zhao, M., Gan, L., Sun, B., He, S., Liu, Y., Liu, L., Li, W., Chen, J., Liu, Y., Zhang, J.*, & Xu, J.* (2024). PeposX-Exhaust: A lightweight and efficient tool for identification of short peptides. Food Chemistry: X, 101249.


[1] 刘万顺,郑淋,李文治,刘磊,岑幸仪,陈天鸽,周梓航,徐巨才,赵谋明PepOSX在食品多肽组学鉴定分析中的应用与评价,现代食品科技,2024.

Patents, 授权发明专利:

[1] 一种基于贝叶斯评价和序列搜库的多肽组学鉴定方法及其应用,ZL202210150460.7已授权

[2] 一种基于多肽长度的短肽组学鉴定方法及其应用,202210151752.2,已授权。

Relavant works:

[1] Xiao Zhou, Liwen Jiang, Qianqian Liu, Xinxin Zhang, Jucai Xu*, Yang Liu*Comparative peptidomics analysis in the discovery of umami peptides from Chinese DouchiFood Chemistry,2024

[2] Wu J, Huang P, Feng Y, Cui C*, Xu J*, Li L*. Enhancing Kokumi Sensation and Reducing Bitterness in Acid-Hydrolyzed Vegetable Proteins through Lactate and Thermal Processing. J Agric Food Chem. 2023 Dec 13;71(49):19694-19704. doi: 10.1021/acs.jafc.3c04282. Epub 2023 Nov 28. PMID: 38016698.

[3] Liqi Ai, Lei Liu, Lin Zheng, Yang Liu, Baoguo Sun, Guowan Su, Jucai Xu*, Yajun Chen*, Mouming Zhao*,An on-line stop-flow RPLC × SEC-MS/DPPH radical scavenging activity analysis system and its application in separation and identification of antioxidant peptides,Food Chemistry,2023,137670.

[4] Wu J, Li Q, Cui C*, Xu J*. Screening of novel bovine elastin derived peptides with elastase inhibition and photoprotective potential: A combined in silico and in vitro study. J Sci Food Agric. 2023 Sep 2. doi: 10.1002/jsfa.12961. Epub ahead of print. PMID: 37658829.

[5] Wu Li, Junhong Huang, Lin Zheng, Wanshun Liu, Liqi Fan, Baoguo Sun, Guowan Su, Jucai Xu*, Mouming Zhao*. 2023. A fast stop-flow two-dimensional liquid chromatography tandem mass spectrometry and its application in food-derived protein hydrolysates. Food Chemistry 406:135000.

[6] Jing Wu, Junpeng Zhao, Yubo Zhou, Chun Cui*, Jucai Xu*, Laihao Li, Yunzi Feng. 2023. Discovery of N-l-Lactoyl-l-Trp as a Bitterness Masker via Structure-Based Virtual Screening and a Sensory Approach. Journal of Agricultural and Food Chemistry 71(4). 2082-2093. 10.1021/acs.jafc.2c07807.

[7] 范丽琪,郁晓艺,刘磊,李武,许思盈,李晓敏*,徐巨才*,肽组学分析技术及其在食品中的应用进展,现代食品科技,2023.