Exhaust: 一个轻量化、高效率短肽鉴定引擎
Paper:Liu, W., Zhao, M., Gan, L., Sun, B., He, S., Liu, Y., Liu, L., Li, W., Chen, J., Liu, Y., Zhang, J.*, & Xu, J.* (2024). PeposX-Exhaust: A lightweight and efficient tool for identification of short peptides. Food Chemistry: X, 101249.doi.org/10.1016/j.fochx.2024.101249
l Identification can be performed without fasta sequence data, and nearly all the short peptides can be identified as long as they exist. Especially suitable for exploration of new bioactive peptides.
l The algorithm was proved of high accuracy with the adjusted accuracy rate reaching 98.55% for the known peptide mixtures.
l Hundreds or even thousands of short peptides could be efficiently identified from the food-derived protein hydrolysates.
短肽鉴定特点(PepOSX-Exhaust):
l 无需蛋白序列库,直接输入长度即可进行解谱,无任何解谱遗漏,适用于各种特殊后修饰多肽或新活性短肽的发掘;
l 拥有更高的多肽检出率及准确率,非人工干预下,准确率>75%,结合人工辅助,准确率可高达98.55%
l 一次分析可轻松解谱成百上千条短肽,基本解决生物医药、食品领域短肽鉴定。